Erg25 Controls Host-Cholesterol Uptake Mediated by Aus1p-Associated Sterol-Rich Membrane Domains in Candida glabrata
The uptake of cholesterol from the host is closely linked to the proliferation of pathogenic fungi and protozoa during infection.For some pathogenic fungi, cholesterol uptake is an important strategy for decreasing susceptibility to antifungals that inhibit ergosterol biosynthesis.In this study, we show that Candida glabrata ERG25, which encodes an